CBD Genesis Cream

Cool, soothing CBD pain cream available in lotion, salve, or roll-on form

$29.99 - $69.99
(93 reviews) Write a Review
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Cream: Comes in a 2oz lotion container.

Salve: Comes in a 2oz twist-tube for easy application.

Roll on: Comes in a 3oz roll on tube with a cooling mint feel.

CBD Genesis Pain Cream:

The market for topical CBD-infused creams has exploded in recent times. Research has shown that cannabinoid receptors from the endocannabinoid system are situated in the skin. This means that cannabinoids such as cannabidiol (CBD) can have therapeutic effects when applied externally.

As the name of this product suggests, CBD-rich creams can help with pains. They are also great for providing relief from inflammation and relaxing muscles, particularly post-exercise. We’ll touch more on these benefits later in the article.

Ingredients used

This CBD topical cream has been made with a full-spectrum CBD extract. The lab reports for both the 500 and 1000mg products confirm the high CBD content of these products, and that the amount of psychoactive THC is below the legal 0.3% limit.

Full-spectrum CBD is made with all of the hemp extract, and therefore contain trace quantities of other cannabinoids and terpenes. There may be limited research on many of these compounds in their individual state, but studies show CBD is more effective when part of a full extract, compared to when taken isolated.

This CBD Genesis Pain Cream is also made with beneficial essential oils, xantham gum and an organic alcohol extract of Salix Alba bark, which is a natural exfoliant for the skin.

Reasons for using a CBD cream

In this section, we’ll cover some general reasons for using the CBD Genesis Pain Cream. This list is not exhaustive, but should give you some guidelines for use.

Chronic pain relief

Lots of CBD products are thought to help with chronic pain - these include edibles, tinctures and e-liquids. However, for targeted relief from pain, topical products stand out. As the CBD stays in one place, the analgesic effects are all concentrated on the area where the CBD was applied. If you are managing lower back pain, for instance, the benefits will all be felt in this region.

How does CBD relieve pain? Scientists are not 100 percent sure on the mechanisms, just that it can have a positive effect. It is perhaps thanks to CBD inhibiting breakdown of the endocannabinoid anandamide (AEA). AEA is a CB1 receptor agonist, a cannabinoid receptor in the ECS that regulates pain sensitivity. Furthermore, CBD is a vanilloid receptor agonist - this receptor is not a part of the ECS, but it does affect how the body feels pain.

Inflammation relief

CBD is an excellent anti-inflammatory, so it’s possible to use CBD for arthritis pain. The two types of arthritis are rheumatoid and osteoarthritis.

Rheumatoid is an autoimmune disease - CBD may help here by restoring regulation to the ECS, and with it the immune system. Osteoarthritis is a result of wear and tear, and CBD can alleviate joint pain, and may work to repair damaged joint cartilage.

The reductive effect of CBD on inflammation means creams could also be used to treat swelling and bruising.

Muscle relaxation

The microscopic muscle tears which can occur after an intense workout are not, contrary to opinion, bad, but they can cause discomfort and soreness. Any of us who exercise are familiar with this pain, but it is manageable with a CBD cream for pain. Lather up, and you’ll help to alleviate the notorious aches which set in after working out.

For skin conditions


CBD Genesis Salve:

Our CBD Genesis topical range is growing, and we are delighted to introduce this CBD twist tube salve, which is made from organic hemp and beneficial for the skin in multiple ways. Cannabidiol (CBD) is making its mark in topical products, with more and more scientific studies identifying that the endocannabinoid system (ECS) has an important role in the skin.

This particular salve is infused with 500mg of CBD-isolate extract, into a 2oz tube. Plenty of other natural ingredients and essential oils have been added to this product to complement the hemp extract. The result is a topical CBD product that is mighty effective and convenient to use. The twist tube means that the salve can be conserved and will continue to work long after you first opened it.

This article will concentrate on the benefits offered by the CBD extract and the other ingredients that we have used to make the salve. We’ll quickly run you through some ECS science, before showing you how to effectively use this product. We hope this CBD salve review will enhance your knowledge of this specific product, and give you a better general understanding of CBD.

Ingredients in this CBD salve

There are many benefits to a hemp flower extract, but we have chosen to go one better by mixing in extracts and oils from other plants too. These ensure that this CBD cream is one of the most therapeutic and effective salve products on the market right now.

CBD-isolate extract from industrial hemp

Industrial hemp has made a huge comeback in the United States over the past few years, after being legalized by the federal government courtesy of the 2014 Farm Bill. Now, it’s completely legal to use hemp extracts which are packed with CBD to make products that are legal across the nation.

Our salve is made purely with the CBD from the hemp, with the cannabinoid removed from all other compounds, leaving a clean isolate extract. CBD-isolate products not only meet federal regulations by having less than 0.3% THC - this salve contains NO THC whatsoever!

Coconut oil

This ingredient is really nourishing and moisturizing for the skin, and also makes the CBD more potent - the fatty acids called MCTs are responsible for this. Coconut oil is fantastic for the skin for a few other reasons: it helps with alleviating inflammation and healing wounds, and the antimicrobial properties are helpful for fighting infections.


Arnica is an ancient, traditional remedy, and its extract serves to bolster the value of our CBD Genesis salve. This plant is also great for reducing inflammation and swelling. Arnica boasts analgesic properties that are brilliant for easing tight muscles, and the stiffness that comes from conditions like arthritis.

Ginger root

Ginger root is considered a superfood, but did you know that it can be just as powerful when applied to the skin? This antioxidant-rich extract may possess anti-aging qualities, by combating a notorious extrinsic aging process called free radical aging. Ginger root is also renowned for having a radiating effect on the skin, which is perfect for brightening up dull and aging skin.


This ingredient provides the skin with a protective layer, but does so without clogging pores and risking infection. Beeswax is a potent anti-inflammatory, like with many of the extracts in this product. It appears to hold further benefits for the skin, facilitating cell reconstruction by virtue of being a rich source of vitamin A.

The science behind applying CBD to the skin

CBD has been mostly viewed as a substance that you consume - therefore, why does it work for the skin? The answer is quite simple. The skin is an organ - the largest in the body - and can absorb various substances, including CBD. After the ECS was discovered in the early 90s, it soon became apparent that receptors from the system were present and active in the skin.

The CB1 receptor is mostly implicated in pain perception, as it is a part of the central nervous system. The CB2 receptor works as the link for the ECS to the immune system. CBD encourages natural regulation at these receptors, delivering its effects in this way, rather than interfering with the ECS and binding directly to CB1 and CB2 receptors.

Uses for this twist tube salve

Please remember that these statements have not been evaluated by the FDA (Food and Drug Administration). CBD oil and CBD salves are not intended to treat, cure or prevent any disease or condition. Please use this product responsibly.

CBD salve for arthritis

Arthritis is sometimes caused by inflammation only, but in the case of rheumatoid arthritis can be a signal of more serious immune system problems. Our CBD salve may have a calming effect on the inflammation, and reduce the damage that arthritis is doing to your joint cartilage. The pain relief aspect of CBD could also help with discomfort in the joints. Salves are really good for arthritis, as they can be used directly on the troublesome area.

CBD salve for back pain

Back pain, knee pain, neck pain, leg pain, any type of pain - this CBD salve could make all the difference for you! While, once again, you could use CBD oil or an edible to manage pain, many users are reporting much better results with topical products that get right to the root of the problem.

CBD salve for tight muscles

You can make tight muscles a thing of the past by liberally administering this CBD salve to the regions which are giving you bother. If tight and sore muscles are a problem after exercise, then using the salve will help to leave you refreshed, relaxed and ready for the rest of the day, or in the mood to settle down for the evening.

Final thoughts

In addition to this CBD salve for sale, CBD Genesis also makes a pain cream that provides similarly effective relief for the skin.

While you should exercise caution with using this pain cream on sensitive skin, it has the potential for helping with less volatile skin conditions. Applying CBD to the skin minimizes the risk of fungal, microbial or bacterial infections, as the cannabinoid helps stop the spread of all three.

Moreover, as a natural anti-inflammatory, CBD may reduce symptoms of psoriasis, acne and eczema. Cannabinoid receptors (in this case, CB2) are found in the skin, which is why CBD topicals can be used to tackle skin-based inflammation.

Pain Cream Range

Creams and topicals are the only CBD-infused products that have a localized effect. When you apply it to the skin, the cannabinoids are kept in the skin, and are not transported around the body in the blood. Therefore, these do not have a direct effect on your mood. However, you may find that your mood improves anyway if the cream helps to relieve your pain. We have two CBD creams for pain, sold in 2oz pots with 250 or 500mg of CBD.


The 500mg cream is good if your symptoms are not too severe. The CBD has a soothing effect on the skin, which is great for relaxing the muscles. It will also help with pain, although to get the benefits make sure you apply at regular intervals.


The 1000mg cream is twice as strong, and is intended for people in search of more potent relief. This CBD pain salve will be more effective at relieving intense, chronic pain, as there is more CBD present to interact with the various receptors - both inside and outside of the ECS - in the skin.

A word of advice

As stated on the packaging of this CBD Genesis product, it should be kept away from the eyes. Ensure that you are only using this product topically, and show due care if applying to sensitive skin. It’s recommended to only use a small quantity of the cream each time, but to apply every four to six hours if necessary.

Final thoughts

Our very own CBD Genesis Pain Cream has all the ingredients required to provide meaningful, cannabinoid-based relief for the skin, helping to improve skin quality and reduce inflammation and pain.

Please note that this CBD Genesis Pain Cream product is not intended to treat, cure or prevent any disease. These statements have not been evaluated by the Food and Drug Administration (FDA).

The contents of this article are purely informational, and serve as an introduction as to how people are using CBD topical alternatives in place of prescription medications. However, this article is not medical advice, and if you are in need of medical help, consult with a physician.

Lab Tests

500mg Cream

1000mg Cream

500mg Salve

93 Reviews Hide Reviews Show Reviews

  • 5
    Customer review

    by Carrol on 15th Oct 2022

    My daughter gave me her jar and I tried it with no explanation, it worked! I will be buying your products from now on. I suffer with Chronic Pain, and have tried EVERYTHING, this is the only thing that works.

  • 5
    Customer review

    by Richard Walton on 7th May 2021

    Works great on body as well as vaping it. Highly recommend.

  • 5
    Customer review

    by Amanda Barrett on 24th Sep 2020

    Worked wonders for muscle pain. Will order again.

  • 5
    Customer review

    by Vicki on 10th Mar 2020

    My husband and I love this cream. We rub it on sore hips, knees, and backs at night. We sleep great and feel great in the morning.

  • 5
    Customer review

    by Richard Gillis on 29th Feb 2020

    I highly recommend this pain cream. I have carpal tunnel syndrome and this helps better than any over the counter medications or cream and the smell is not too strong just right.

  • 5
    Customer review

    by Catherine on 28th Feb 2020

    Pain s gone every time I use this cream!! Love, love, it!!!

  • 5
    Customer review

    by Ivy Reynolds on 12th Feb 2020

    From a surgery perspective: I purchased the 500mg. I had a double mastectomy with a scarless latissimus dorsi flap reconstruction. The area above my breasts "burn" from the inside and my skin is terribly sensitive to the touch. I applied a thin layer to my chest. It works. The relief lasted about 30 minutes. My husband also applied a liberal amount to the areas around (not on) the incisions on my back. Very effective with the stinging & pulling pains. Lasted over an hour. The smell is just ok and in my opinion needs improvement.

  • 5
    Customer review

    by John on 2nd Feb 2020

    Excellent cream. It helped my arthritic pain like nothing else I have found on the market. Highly recommend this product.

  • 5
    Customer review

    by Tallula on 25th Jan 2020

    I really enjoyed both products. I\'ve used this cream before and it really works, I was not able to find a substitute in Nashville so I had to go with this cream, it\'s awesome.