The Ultimate CBD Vape Cartridge Buyer’s Guide for 2022

Vaping is among the most common ways of consuming CBD, with vape carts especially popular. Manufactured to deliver fast-acting effects with no hassle, CBD vape cartridge products appeal to inexperienced and seasoned vapers.

In this buyer’s guide, we will explore the different vape carts on the market and the best products for sale at CBD Genesis. We will also discuss the benefits of vaping cartridges and examine why people use these products.

But let’s begin with an overview of CBD, the substance at the heart of these vape carts!

An Introduction to CBD

An Introduction to CBD

Cannabidiol (CBD) is a naturally occurring phyto-cannabinoid found in cannabis, sought-after for its non-intoxicating nature and therapeutic effects. CBD is the second-most common of the 113 known cannabinoids. 

While not psychoactive like THC, CBD also engages with the endocannabinoid system (ECS). CBD is not an agonist of the CB1 or CB2 receptor but may improve ECS functioning by regulating the body’s endocannabinoid levels.

Hemp-derived CBD is a federally legal substance in the U.S. However, CBD must be derived from hemp plants with less than 0.3% THC. Likewise, finished products must also comply with this THC threshold, as set by the 2018 Agriculture Improvement Act (Farm Bill).

What is a CBD Vape Cartridge?

The vape juice in prefilled CBD cartridges differs from that in standard e-liquids. Cartridges don’t require – and should not have – a carrier oil, and rarely do they contain non-cannabis flavorings.

Instead, the small CBD cart tank should consist of highly-potent CBD distillate and a natural terpene profile. Avoid carts made with diluting vegetable glycerin (VG) or propylene glycol (PG). 

While not dangerous, these cost-cutting ingredients reduce the amount of CBD in a cartridge and offer no benefit. Don’t buy vape carts mixed with MCT oil, either. Scientists don’t know if the widely-used tincture oil ingredient is safe when vaporized.

Most cartridges have a plastic or glass tank and hold 0.5 or 1ml of concentrated CBD e-liquid. Nowadays, nearly all brands make carts with 510-threaded screws to ensure they fit with all regular vape batteries. 

Types of CBD vape cartridges

All cartridges contain one of three types of hemp extract. All produce similar CBD effects, but the subtle differences can affect whether a cartridge is suitable for you.

CBD-isolate: Vape carts made with CBD-isolate only have CBD, with no other cannabinoids present. Some manufacturers mix in terpenes for flavor and fine-tuned effects, but the lack of minor cannabinoids means there is no entourage effect. 

Here’s the good news: CBD-isolate extract is THC-free, so there is no risk of failing a drug test. Furthermore, CBD-isolate carts are generally the cheapest of the three. 

Full-spectrum CBD: Draw upon every hemp benefit with full-spectrum CBD cartridges. Whole-plant hemp extract incorporates minor cannabinoids, legal levels of THC, and cannabis-derived terpenes (CDTs) for optimum therapeutic effects.

Expect to pay a little more for full-spectrum carts, given they have extra beneficial compounds and bring the entourage effect into play. And because the extract can have up to 0.3% THC, full-spectrum carts can potentially make you fail a drug test.

Broad-spectrum CBD: Forget about positive drug tests with broad-spectrum CBD vape cartridges. The cleverly concocted hemp extract preserves the CBD and secondary cannabinoids but filters out all the THC.

Therefore, broad-spectrum hemp has effects comparable to full-spectrum hemp while giving you the same peace of mind as a CBD-isolate product.


Many CBD vape oil cartridges contain natural aroma molecules known as terpenes. These can have relaxing, energizing, or finely balanced properties and complement the hemp to produce highly specific experiences.

Brands use CDTs or botanically-derived terpenes (BDTs) in cartridges. Cannabis-derived terps are more authentic but costlier to obtain. BDTs are a cheaper and increasingly common alternative – and crucially, they still have natural origins.

Every CBD vape cartridge with terpenes falls into one of the following categories.

Sativa: These carts lean toward uplifting, energizing, and cerebral effects. For daytime CBD relief, improved focus, or a fatigue-busting pick-me-up, choose a cartridge infused with sativa terpenes.

Indica: Need a CBD vape cartridge for sleep? I recommend products blended with soothing indica terpenes. The calming properties are deeply relaxing, easing stress and anxiety while relieving aches, pains, and muscle tension.

Hybrid: Purchase a hybrid CBD cartridge if you want a vaping product for all situations. The mixture of sativa and indica terps makes for well-balanced effects – you will feel at ease, but never sluggish, and alert without being on edge.

What is the Best CBD Vape Cartridge?

What is the Best CBD Vape Cartridge?

It’s a subjective question, and the best cartridge for one user might be unsuitable for another. But the cream still rises to the top, with the leading CBD cart brands going the extra mile on product quality. Let’s check out the top cartridges at CBD Genesis.

CBD For The People – 65% Uncut Wax Cartridges (X2)

The CBD vape oil cartridge from CBD For The People contains 500 or 1000mg of delightful hemp extract at a whopping 65% CBD – twice that of their original carts! And as a full-spectrum product, the entourage effect is out in full force!

Choose from a dozen delightful strains and sativa, indica, and hybrid effects. Whether you fancy stress-relieving relaxation or an invigorating energy boost, these guys have you covered in the purest and most potent way possible.

CBD For The People always maximize hemp’s benefits by conserving every useful component of the plant in an unrefined and uncut extract. But that means accepting trace amounts of THC and the slim possibility of a positive drug test.

Terpene strain: Blue Dream (Sativa), Durban Sour (Sativa), Green Cush (Sativa), Blue Cheddar (Indica), Grandaddy Purple (Indica), Orange Cookies (Indica), Strawnana (Hybrid), Super Lemon Haze (Hybrid), White Widow (Hybrid), and more!


  • Ultra-effective uncut and unrefined hemp extract
  • Massive variety of strains
  • 3 built-in variable voltage settings
  • Made with organic, non-GMO hemp
  • Third-party lab tested 

Active CBD Oil – Distillate Cartridges (550mg)

Sample a safe, effective, and powerful CBD vaping experience with a 550mg distillate cartridge from Active CBD Oil. The high-flying brand uses premium-grade Colorado hemp and a ceramic cartridge for maximum potency and vaping purity.

Unlike inferior manufacturers, Active CBD Oil never includes carrier oils, cutting agents, or other additives in their carts. Interestingly, they don’t add terpenes, which eliminates the familiar cannabis flavor, but also that notoriously pungent aroma.

Active CBD Oil’s CBD Distillate Cartridges are THC-free and the safe choice if you could get drug tested. The company also makes the same product in a half-strength 275mg version. This is a third-party tested broad-spectrum CBD vape cartridge. 


  • Made with premium Colorado-grown hemp
  • Fully ceramic cartridge with no toxic heavy metals
  • No PG, VG, MCT, or any other additives
  • 510-threaded screws for near-universal battery compatibility
  • Third-party lab tested 

CBD For The People – 65% CBD Vape Pods (X2 Uncut)

Indulge in CBD For The People’s record-breaking full-spectrum hemp extract with these convenient and portable vape pods. The punchy pods come in 12 excellent strains with 30 aromatic and flavorful terpenes packed into each.

You will need CBD For The People’s Smart Battery Kit to operate the pods. We have multiple kits for sale at CBD Genesis, all designed with buttonless and smart voltage technology for stress-free vaping and seamless on-the-go use.

We recommend these CBD vape pods for experienced vapers only. The small disposable canisters pack a mighty punch, thanks to the winterized, non-GMO, CBD-rich hemp extract. Both the vape juice and the device are third-party tested.

Terpene strain: Durban Sour (Sativa), Green Cush (Sativa), Pineapple Express (Sativa), Grandaddy Purple (Indica), OG Kush (Indica), Orange Cookies (Indica), Strawnana (Hybrid), White Fire OG (Hybrid), White Widow (Hybrid), and more!


  • Wide range of strains with CDTs
  • Free from additives, artificial flavorings, and cutting agents
  • Made with raw, uncut, and unrefined hemp extract
  • Choose from several stylish smart battery kits with buttonless technology
  • Third-party lab tested 

Benefits of CBD Vape Cartridges

Benefits of CBD Vape Cartridges

For the avoidance of doubt, this section discusses the benefits of vape cartridges over other CBD products rather than the benefits of vaping CBD itself.

Fast-acting effects

Carts have a super-fast onset of effects and provide speedier relief than other CBD product types, including tincture oils, capsules, and edibles. That’s a convenient quality but also vital if you have issues that come on suddenly and severely.

When using a vape cartridge, you inhale the cannabinoids into your lungs, which get absorbed into your bloodstream within seconds. The CBD then disperses around the body, including past the blood-brain barrier, and starts doing its thing!

That said, fast-acting effects also mean a shorter overall experience. You will require regular top-ups to enjoy unbroken CBD effects throughout the day. 

Less hassle than e-liquid vaping

CBD cartridges are simpler to vape than bottled CBD e-liquids, which makes them ideal for first-time users. Prefilled and ready-to-vape, you only need a compatible battery to enjoy 510-threaded CBD cartridges.

Unlike e-liquid vaping, cartridges don’t demand regular maintenance and cleaning to function at optimum levels. Cartridges occasionally clog, but it’s a minor issue. And as a single-use product, you don’t have to worry about repairing or replacing parts.

Keep your battery charged and enjoy hassle-free CBD cartridge vaping wherever you are. These sleek and slender devices are perfectly portable and suited for on-the-go vaping, unlike bulky tank vapes. 

Less risky than smoking

Vaping CBD is less harmful than smoking it. Even though smoking CBD flower is less dangerous and addictive than smoking tobacco, it is still harmful. And while CBD vaping is not 100% safe, it’s not as risky as any kind of smoking.

Given vaping and smoking both deliver instantaneous CBD effects, smoking has no therapeutic advantage. Unless you have a personal preference for puffing joints and blunts (which some do!), you are better off getting your CBD dose by vaping carts.

More discreet than smoking

Smoking and vaping provide identical CBD experiences, but the latter is much more discreet. Laying back and sparking up a joint may be okay in the comfort of your own home, but it’s not a feasible way to consume CBD in a public space.

In contrast, vapor has a less potent smell than smoke and dissipates faster, making it easier to get your hit when out and about. Sure, you cannot vape everywhere, and CBD vapor still has a weed-like aroma, but it’s less smelly than smoke from a joint. 

Long shelf life

Prefilled and sealed CBD vape cartridges have an impressive lifespan and can stay in peak condition for up to a year with the correct storage. In contrast, opened edible and tincture oil products and loose CBD flower can degrade quickly.

Vape cart durability also means perfect storage less of a priority. Keep unused products in the packaging and store opened vape carts in a dark, cool place.

Consistently brilliant hits

When vaping cartridges, you can expect solid and satisfying hits every time – an assurance you don’t have when smoking CBD joints or blunts. Each cartridge hit is as flavored and intense as your first, even as the vape juice runs down.

Indeed, some CBD vape pen cartridges emit a standardized amount of CBD with every draw, so you can regulate your intake with precision. Smokable products and standard CBD e-liquids don’t have these perks.

Why Do People Vape CBD Cartridges?

Why Do People Vape CBD Cartridges?

CBD’s endocannabinoid system influence makes it an appealing substance for various reasons. But why do people turn to vape cartridges specifically? Let’s explore how rapid-acting CBD cartridges may enhance your wellbeing. 

Pain relief

Vaporized CBD has a near-instant effect, which is useful for dealing with pain flare-ups. If you suffer sharp, unpredictable bursts of discomfort, you need a CBD product that acts swiftly to provide relief – and vape carts serve this purpose well.

CBD is not a proven solution for pain. However, research indicates ECS involvement with pain perception, and studies suggest CBD may relieve inflammatory and neuropathic pain.

Stress relief

CBD is an effective stress-buster, which could have several indirect health benefits. Experts know high stress puts the body under strain and is an underlying cause of many ailments. CBD could combat several health issues by tackling stress at the source.

For the best relaxation and relief, choose an indica CBD vape cartridge. Soothing indica terpene profiles pair beautifully with CBD to relieve physical and mental tension and promote an all-round tranquil state. 

Improve mood

Part of being human is enduring days where you don’t feel at your best. But CBD-infused cartridges can help you forget about any troubles and break out of a slump.

CBD is a promising mood-booster that improves your frame of mind without inducing psychoactive effects and heady euphoria like marijuana. Hence, you can harness CBD to enhance your mood while remaining in full control of yourself.

Boost energy levels

As a biphasic compound, CBD has dose-dependent effects. While typically described as a relaxing substance, CBD is surprisingly energizing in low amounts – and a hit or two on a vape cart can give you a mental and physical lift.

Capitalize on these underrated benefits with a sativa CBD vape cartridge. The energy-boosting terpenes will work with a small CBD serving to maximize the cannabinoid’s wakeful properties.

CBD Vape Cartridges vs. CBD Disposable Pens

CBD cartridges and disposable vape pens have much in common. Both generate fast-acting effects, come in various strains, and contain identical high-strength CBD extracts. So, what is the difference, and which is best?

Essentially, vape cartridges attach to a separate, rechargeable battery, whereas disposables have a single-use, built-in battery. CBD disposable pens offer even more vaping convenience, but they cost a few bucks extra.

I recommend cartridges for seasoned vapers who enjoy switching between CBD strains or cannabinoids, and disposable pens for newbies. If you vape regularly, it makes more sense to invest in a 510-threaded battery and change the cartridge as required.

For those unconvinced or merely curious about vaping, it’s cheaper to buy a disposable pen than to purchase a cartridge and battery separately. Of course, you may also prefer disposables if you don’t want the bother of charging a vape battery! 

Where to Get CBD Vape Pen Cartridge Products

Where to Get CBD Vape Pen Cartridge Products

CBD Genesis stocks a selection of CBD vape cartridges, including those mentioned earlier in this buyer’s guide. The carts we sell are third-party tested, super-potent, and free from additives, cutting agents, carrier oils, dilutants, thinners, and solvents.

Choose CBD Genesis for a seamless shopping experience, affordable vape carts, and unmatched customer service. Spend $50 or more and we will ship your order free of charge!

Interested in buying CBD vape cartridges in bulk for your business? CBD Genesis operates a wholesale service and we would love to work with you! 

Register for a wholesale account to receive access to our product catalog. Please note that we have a $250 minimum order policy for wholesale purchases.

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